Cadence announced an expansion of its collaboration with NVIDIA to advance agentic AI solutions for IC and system design. The updated portfolio integrates Cadence’s chip and system design tools with NVIDIA’s accelerated computing stack, including Grace CPUs and Blackwell GPUs, to support autonomous, long-running agents that handle design intent translation, automated flows, design generation, error debugging, and end-to-end workflow management.

The solutions are available as turnkey deployments on the Cadence Millennium M2000 Supercomputer, which combines NVIDIA Grace Blackwell systems. Cadence reports up to 80X greater throughput and up to 20X lower power consumption compared to previous configurations. The expanded accelerated offerings cover analysis, optimization, and design, with key solvers optimized using NVIDIA CUDA-X.
Performance examples include the Cadence Clarity 3D Solver, where a Millennium M2000 system with 8 NVIDIA RTX Pro 6000 GPU servers achieves up to 5X faster extraction for complex, large-scale designs, or 4X better cost iso-performance than equivalent CPU-based systems.
Cadence accelerated solutions scheduled for availability in 2026 include:
Electronic Design Automation (EDA): Innovus Implementation System for place-and-route; Celsius Thermal Solver and Voltus IC Power Integrity Solution for chip, chiplet, and 3D-IC analysis and optimization; EMX Planar 3D Solver and Liberate MX Memory Characterization for advanced memory and circuit analysis; Spectre X Simulator and Quantus Field Solver for circuit analysis.
System Design Automation (SDA): Allegro X Design Platform for advanced package and PCB optimization; Clarity 3D Solver and Celsius EC Solver; Fidelity CFD Software for system-level multiphysics analysis; MSC Actran for physical AI system analysis and optimization.
Life Sciences / Bio: ROCS X for AI-enabled virtual screening of over 200 trillion drug-like molecules in 3D searches; Target X for physics-based detection of druggable pockets with over 90% success rate.
The Cadence Allegro X Design Platform and Cadence Reality Digital Twin Platform integrate with NVIDIA Omniverse libraries for photo-realistic visualization. Cadence MSC Virtual Test Drive (VTD) is being integrated with NVIDIA Cosmos and NVIDIA Omniverse NuRec for physical AI advancements.
Cadence’s agentic AI solutions are led by the Cadence ChipStack AI Super Agent for higher-quality, more complex designs. The companies are collaborating on future agentic AI innovations in custom and analog design, and on NVIDIA NemoClaw, an open-source stack for running OpenClaw always-on assistants with NVIDIA OpenShell runtime and models such as NVIDIA Nemotron.
Customer applications include:
Honda uses Cadence Fidelity CFD Software on the Millennium M2000 GB200 NVL72 system for time-accurate, full turbofan engine simulation.
Micron integrates GPU-accelerated Cadence design technologies and agentic AI into its HBM memory design flow to reduce iteration cycles while maintaining accuracy.
Larsen & Toubro Semiconductor applies the Cadence Spectre X Simulator, accelerated up to 5X with NVIDIA GPUs, to shorten design cycles for AI and data center chips.
Anirudh Devgan, president and CEO of Cadence, stated that the collaboration combines Cadence’s agentic IC design and physics-driven optimization with NVIDIA’s accelerated computing for AI-driven chip innovation.
Jensen Huang, founder and CEO of NVIDIA, described the Cadence Millennium M2000 as a revolutionary AI supercomputer for designing next-generation infrastructure.
Additional details are available at https://www.cadence.com/en_US/home/company/nvidia.html.






